Gender differences in autoimmune disease
نویسندگان
چکیده
منابع مشابه
Gender differences in autoimmune disease
Autoimmune diseases are a range of diseases in which the immune response to self-antigens results in damage or dysfunction of tissues. Autoimmune diseases can be systemic or can affect specific organs or body systems. For most autoimmune diseases there is a clear sex difference in prevalence, whereby females are generally more frequently affected than males. In this review, we consider gender d...
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Autoimmune diseases affect approximately 8% of the population, 78% of whom are women. The reason for the high prevalence in women is unclear. Women are known to respond to infection, vaccination, and trauma with increased antibody production and a more T helper (Th)2-predominant immune response, whereas a Th1 response and inflammation are usually more severe in men. This review discusses the di...
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ژورنال
عنوان ژورنال: Frontiers in Neuroendocrinology
سال: 2014
ISSN: 0091-3022
DOI: 10.1016/j.yfrne.2014.04.004